翻訳と辞書 Words near each other ・ Internal communications ・ Internal conflict ・ Internal conflict in Azawad ・ Internal conflict in Bangladesh ・ Internal conflict in Myanmar ・ Internal conflict in Peru ・ Internal conflict in South Sudan ・ Internal conflict in Yemen ・ Internal consistency ・ Internal consistency of the Bible ・ Internal control ・ Internal control region ・ Internal conversion ・ Internal conversion (chemistry) ・ Internal conversion coefficient ・ Internal Coordinate Mechanics ・ Internal debt ・ Internal devaluation ・ Internal discourse ・ Internal Dobrujan Revolutionary Organisation ・ Internal documentation ・ Internal dosimetry ・ Internal drainage board ・ Internal Drive ・ Internal drive propulsion ・ Internal elastic lamina ・ Internal energy ・ Internal entrepreneur ・ Internal erosion ・ Internal Exile Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Internal Coordinate Mechanics ： ウィキペディア英語版 Internal Coordinate Mechanics ICM stands for Internal Coordinate Mechanics and was first designed and built to predict low energy conformations of molecules by sampling the space of internal coordinates (bond lengths, bond angles and dihedral angles) defining molecular geometry. In ICM each molecule is constructed as a tree from an entry atom where each next atom is build iteratively from the preceding three atoms via three internal variables. The rings kept rigid or imposed via additional restraints. ICM also is a programming environment for various tasks in computational chemistry and computational structural biology, sequence analysis and rational drug design. The original goal was to develop algorithms for energy optimization of several biopolymers with respect to an arbitrary subset of internal coordinates such as bond lengths, bond angles torsion angles and phase angles. The efficient and general global optimization method which evolved from the original ICM method is still the central piece of the program. It is this basic algorithm which is used for peptide prediction, homology modeling and loop simulations, flexible macromolecular docking and energy refinement. However the complexity of problems related to structure prediction and analysis, as well as the desire for perfection, compactness and consistency, led to the program's expansion into neighboring areas such as graphics, chemistry, sequence analysis and database searches, mathematics, statistics and plotting. The original meaning became too narrow, but the name was kept. The current integrated ICM shell contains hundreds of variables, functions, commands, database and web tools, novel algorithms for structure prediction and analysis into a powerful, yet compact program which is still called ICM. The seven principal areas are centered on a general core of shell-language and data analysis and visualization. ==See also== * ICM-Browser 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Internal Coordinate Mechanics」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.